Regenerative Aesthetics

Exosome Therapy

Exosome therapy applies concentrated regenerative signalling molecules to the skin, usually straight after microneedling, to support repair, calm and recovery while your channels are open.

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Exosome therapy applied after microneedling at Perfectus Derma, Soho

The short answer

What this treatment is

Exosomes are tiny messengers that cells use to communicate, carrying signals that support repair and renewal. At Perfectus Derma in Soho, we use Purasomes and Secretomes, applied topically to the skin rather than injected, because in the UK exosomes are used as a topical treatment. We usually pair them with SkinPen microneedling: once the tiny channels are created, the exosome serum is applied so it can reach deeper into the skin while it is most receptive. The aim is to support the skin's natural recovery, calm redness after a procedure and enhance the quality of your results. Evidence for exosomes is still emerging, so our nurses use them thoughtfully as part of a wider regenerative plan, always after a face-to-face consultation.

Areas treated

What's included

Applied topically after microneedling to reach receptive skin
Supports the skin's natural repair and recovery
Helps calm redness and inflammation after a procedure
Complements microneedling, polynucleotides and other regenerative treatments
Uses Purasomes and Secretomes, handled by NMC-registered nurses
No injectable medicine involved, applied to the skin surface

Boundaries of practice

What's not treated

Good practice means saying no when indicated:

Pregnancy or breastfeeding
Active skin infection, inflammation, eczema or cold sore at the treatment site
Active or severe acne, assessed before treatment
Bleeding disorders or use of blood-thinning medication without clearance
Keloid or hypertrophic scarring tendency
Under 18 years of age

Patient journey

What to expect

Consultation & preparation

Avoid ibuprofen, aspirin, alcohol and harsh actives such as retinoids for a few days before your session, as advised. Arrive with clean skin and no make-up. Tell your nurse about any recent skin treatments, cold sores or active breakouts at your consultation.

During treatment

What are exosomes and how do they work?

Exosomes are microscopic vesicles that cells release to send signals to one another. In skincare, the signals they carry are linked to repair, renewal and calming inflammation. The exosomes we use are laboratory-produced and applied to the surface of the skin, where they support the natural processes that rebuild and refresh it. Because the science is still developing, we describe exosomes honestly as a promising regenerative treatment rather than a cure for any condition.

Why are exosomes applied after microneedling?

Freshly microneedled skin has thousands of temporary microscopic channels. Applying the exosome serum immediately afterwards, while these channels are still open, allows it to reach beyond the surface and work where the skin is actively repairing. This is why we offer exosomes together with SkinPen microneedling: the two treatments are designed to complement each other, with microneedling stimulating collagen and exosomes supporting the recovery that follows.

What does an exosome session involve?

Your session begins with a face-to-face consultation and skin assessment. After numbing, your nurse performs SkinPen microneedling, then applies the exosome serum across the treated area. The whole appointment takes around 60 minutes. You can expect some redness and warmth, similar to mild sunburn, for a day or two. A short course is usually recommended for the most noticeable improvement in skin quality.

Where can I have exosome therapy near me in central London?

Perfectus Derma is inside UNTIL Soho at 111 Charing Cross Road, a short walk from Tottenham Court Road and Leicester Square stations. Every course starts with a consultation so our nurses can confirm that exosomes with microneedling, or another regenerative treatment, is the right choice for your skin and goals.

Aftercare

Redness and warmth settle within 24 to 72 hours. Avoid make-up, saunas, swimming and direct sun for the first day or two, and use a gentle cleanser and SPF. Your nurse will confirm when to restart your usual skincare and any further sessions.

Pricing

Transparent, all-in pricing

Exosome therapy with microneedling

Exosomes with microneedling: 1 session

£300

Exosomes with microneedling: course of 3

£810

Regenerative combination (exosomes, polynucleotides and microneedling)

Regenerative combination: 1 session

£450

Regenerative combination: course of 3

£1,200

FAQ

Common
questions

Are exosomes injected?

No. In the UK, exosomes are applied topically to the surface of the skin, not injected. We apply them immediately after SkinPen microneedling, so the freshly created channels help them reach deeper into the skin. This approach keeps the treatment gentle while allowing the exosomes to work where recovery is most active.

What can exosome therapy help with?

Exosomes are used to support the skin after microneedling, helping to calm redness and encourage repair while improving overall texture and radiance. They are best thought of as a way to enhance the results of a regenerative treatment plan. Evidence is still emerging, so we use them as a complement, not a standalone fix.

Is there downtime after exosome therapy?

Because exosomes are paired with microneedling, the downtime is the same as microneedling alone. Expect redness and a feeling of warmth, much like mild sunburn, for 24 to 72 hours. Avoid make-up, sun exposure and harsh skincare for the first day or two, and always protect the skin with SPF.

How many exosome sessions will I need?

Most people have a course of three sessions for the clearest improvement in skin quality, though a single session can be a lovely boost before an event. We also offer a regenerative combination with polynucleotides and microneedling. Your nurse recommends the right plan for your skin at your face-to-face consultation.

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Perfectus Derma Aesthetics • 111 Charing Cross Road, London WC2H 0DT

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Appointments typically available within 1–2 weeks